Established as the Bible of Rheumatology, this definitive two-volume reference is now in its thoroughly updated Fifteenth Edition. More than 200 of the world?s preeminent experts provide encyclopedic coverage of the entire field of rheumatology, including relevant basic science, diagnostic and therapeutic modalities, and pathophysiology, diagnosis, and medical and surgical management of all rheumatic diseases and syndromes. Chapters include extensive references and more than 1,200 illustrations complement the text. A new co-editor, Dr. Larry Moreland, joins Dr. Koopman for this edition. Coverage includes numerous new treatment modalities, a new chapter on anti-TNF drugs, and cutting-edge molecular and genetic research.