żNew key points boxes and clinical algorithms for each chapterżWill contain Authorżs Preferred Management Approach to each chapter. żNew information on transfusion medicine and transplantation added throughout żMore illustrations that elucidate molecular pathways and pathophysiologic changes in disease. żFocus still onBasic science and molecular biology that really matters to readership|żCovers all chemotherapy and supportive care regimens in detailżWill be more prescriptive than ever. żNow also very clinically oriented and prescriptive. All about precise drug dosages and potential combinations for tailoring multi-drug regimens. żAll diseases covered in detail. More enhanced coverage of thrombosis and hemostasis this edition żWill also now cover all drugs about to enter onto the horizon of clinical practice as well(Biologic and immunologic therapies)