The investigation and treatment of hypertension, a leading risk factor for cardiovascular disease throughout the world, remains a challenge, even in developed countries. Although antihypertensives have been available for 50 years, the rational and effective use of the myriad of existing drugs remains a concern, as does the desire to identify patients with secondary hypertension from the mass of individuals with primary or essential hypertension. The aim of this handbook is to provide state-of-the-art information concerning the pathophysiology, diagnosis, investigation and management of hypertension in the 21st century. The book covers the underlying physiological, genetic and environmental components which may contribute towards its pathogenesis as well as the currently available therapies and clinical trials in hypertension. The chapters are clearly laid-out and written for the non-expert but contain sufficient detail to serve as a useful reference for the experienced physician. The book is completely up-to-date and evidence-based, while the authors are recognized experts in hypertension based at one of Europe's leading hypertension centres. * A practical and comprehensive guide to this challenging area of medicine * Covers the pathophysiology, diagnosis, investigation and management of hypertension * Follows the patient's path from referral and initial investigation to recommended paths of management * Completely up-to-date and evidence-based describing the roles of new approaches to hypertension management * Fully illustrated with numerous diagrams, graphs and colour plates to aid understanding * Written by recognized experts at one of Europe's leading hypertension centres