Incorporates the most recent advances in basic and clinical immunology - emphasizing diagnostic and clinical applications as well as state-of-the-art discussions of the principles and strategies for modulation of the immune response and treatment of hypersensitivity, autoimmune, and immune deficiency diseases. Includes clinical case studies as well as end-of-chapter questions - in the USML multiple choice format - for self-evaluation and preparation for licensure and specialty boards.