This book is written for pathologists, medical researchers, and other laboratory personnel working within the field of pathology. The book is divided into seven chapters: immunocytochemistry, in situ hybridization, polymerase chain reaction, preparatory techniques for flow cytometry, quantitative staining methods for image cytometry, skeletal muscle enzyme histochemistry, and preparatory methods in cytopathology. For each method there are detailed discussions of principles, techniques, reagent preparations, results, errors, and artifacts. Laboratory technicians will be able to follow the procedures in a stepwise manner. Of particular interest to pathologists are illustrations of artifacts that appear in certain reactions, e.g. immunohistochemistry. These will help to pinpoint errors for corrective action in the laboratory. There are 254 pages, 18 tables, 5 color plates, and 365 black-and-white illustrations. The quality of hoth clinical and microscopic illustrations is out-standing. Gynecologists as well as pathologists will find it indispensable. The text is 254 pages in length and contains 99 descriptive color illustrations. The bibliography is up-to-date, but also includes classical references. This book will be an indispensable and practical reference in any pathology laboratory as it includes established as well as developing methods, such as in immunohistochemistry, cytometry, and molecular biology, under one cover. It is printed on heavy paper, and is designed as a bench manual with binding that will allow the book to lie flat.