Basic Concepts of Bioinformatics

Bioinformatics is a computer based discipline which deals with the acquisition, storage, management, access and processing of data of molecular biosciences, and started with the networking of computers and accumulation of data on genes and proteins in biotechnology. It has achieved significant role with the availability of new DNA sequencing protocols and the presence of high memory desktop Computers that help in storing and analyzing the data sequences. Today, it is paramount importance to whole world, in general, but particular for developing and under developed countries, because if the vast potential by genomic technologies in elaborating the process of drug development. Diagnosing and curing diseases have always been and will continue to be an art. The reason probably will living organism, in general, and humans in particular, are regarded as complex networks of molecular interactions that fuel the processes of life. This "molecular circuitry" has intended modes of operation that correspond to diseased states. In molecular medicine, the goal of diagnosing a disease is to identify its molecular basis, i.e., to answer the question what goes wrong in the molecular circuitry. The goal of therapy is to guide the biochemical circuitry back to healthy state. The molecular basis of life is formed by complex bio-chemical processes that constantly produce and recycle molecules and do so in highly coordinated and balanced fashion the molecular basis of a disease ties in modifications of the action of these biochemical pathways.