This volume covers the first full year of experimental design topics at the beginning graduate level with a well balanced, down-to-earth, and complete presentation, covering both design and analysis equally. Mathematical rigor is kept to a minimum with up-to-date discussions on hard-to-change factors, the selection of factor levels in terms of physical units, designs with more than one response variable, and multi-response optimization are also included due to the intense applicability to the industrial sector.