Shinrei Tantei Yakumo (Psychic Detective Yakumo) tells the story of a college student, Saitou Yakumo, who was born with two different eye colors. His red (left) eye enables him to see ghosts and spirits. Yakumo believes ghosts and spirits are bound to earth because of a certain "cause" (e.g. their killer getting away clean, etc.) and by eliminating that "cause" the spirits will be able to rest in peace. Finding an unlikely friendship in Ozawa Haruka after her request for help, Yakumo, with Haruka, begins to unravel mysteries behind the dead.