This 4th Edition conveniently compiles the state-of-the-art expertise of more than 275 authorities under one cover! The New Edition of this classic critical care text has been updated and expanded to reflect the most current, clinically relevant information available...and reorganized so life-threatening conditions first are presented first.* contributions from over 275 experienced authorities in the care of the critically ill.* Places chapters on life-threatening conditions in the first section, paralleling clinical practice.* Includes a new section on Renal/Nephrology, as well as new chapters on heat stroke, hyperthermia, transfusion therapy, trauma care of the elderly, mediators of multi-organ failure in sepsis, gene therapy, and much more.* Reorganizes the endocrinology, metabolism, nutrition, and pharmacology subsections from the 3rd Edition into one separate section.* Presents expanded and reorganized sections on issues in patient care and ethical problems.* Features abundant tables and illustrations and algorithms that clarify and enhance the text.