Vanilloid Receptor TRPV1 in Drug Discovery

Arthur Gomtsyan, Connie R. Faltynek
Vanilloid Receptor TRPV1 in Drug Discovery
Vanilloid Receptor TRPV1 in Drug Discovery
Vanilloid Receptor TRPV1 in Drug Discovery
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Opis

Examines the emerging therapeutic role of TRPV1 TRPV1 is considered an integrator of noxious stimuli and therefore may be at a crossroads for pain transmission pathways. Because of its potential for managing multiple pain types, including osteoarthritis, chronic low back pain, neuropathic pain, and cancer pain, some consider it "the holy grail" of pain management. This dedicated reference summarizes available data related to the potential therapeutic utility for TRPV1 ligands. With contributions from many of the world's leading experts on TRP channels, Vanilloid Receptor TRPV1 in Drug Discovery covers the important TRPV1 target for drugs to treat painful conditions such as inflammation, arthritis, and cancer pain. The book discusses:Recent advances in biology, chemistry, and pharmacology at both the preclinical and clinical stage of the dynamic area of TRPV1 drug discovery researchThe potential for drugs targeting TRPV1 in painful conditions such as inflammation, arthritis, and cancerThe development of analgesic drugsOther applications for TRPV1, including the treatment of respiratory disease and diabetes
Data wydania: 2010-03-01
ISBN: 978-0-470-17557-6, 9780470175576
J─Özyk: angielski
Wydawnictwo: John Wiley & Sons
Kategoria: Medycyna
Stron: 488

Autor

Arthur Gomtsyan ARTHUR GOMTSYAN is an Associate Research Fellow at Abbott Laboratories where he focuses on neuroscience research and pain drug targets. He is on the editorial board of two peer-reviewed journals and has over forty scientific articles to his credit. ...

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