Meta-analysis of Binary Data Using Profile Likelihood

Provides an overview of the analysis of data from multicenter clinical studies using the profile likelihoodIncludes an introductory chapter reviewing several multicenter studiesPresents real examples to support theoretical toolsFeatures examples computed using software that can be downloaded from the Web With multicenter clinical trials becoming increasingly prevalent in the evaluation of the efficacy of medical treatments, Analysis of Multicenter Studies Using Profile Likelihood provides an overview of this methodology, a type of statistical method that has proven to be a powerful tool for analyzing data from multicenter studies. The author presents a wide range of real examples of multicenter studies to support the theoretical tools and information discussed throughout the text. These examples are computed using software that is available for download from the Internet. Ideal for researchers, the text also includes an introductory chapter that offers a review of several multicenter studies.