Tenma is lying low, but his brief respite is doomed to be short-lived. Milan, one of Tenma's new friends, is planning to assassinate a man with deep ties to "Red Rose Mansion." Can Tenma dissuade him from this drastic line of action? Also, a seemingly unrelated string of murders by various serial killers hints at a sinister connection with Johan. How many more people need to die before the monster's work is complete?