The vast progress made in the investigation of biomolecules using NMR has only recently been rewarded with the Nobel Prize for Kurt Wüthrich. Edited by a former coworker of Wüthrich, this book present...
Most pharmaceutically active compounds possess a chirality that greatly influences their pharmacological properties. Since all pharmaceutical products nowadays are produced in chirally pure form, this...
Here, expert scientists from industry and academia share their knowledge on the assembly of functional human tissues in vitro and how to design drug screenings predictive of human exposure. In so doin...
This first comprehensive survey to cover all pharmaceutically relevant topics provides a comprehensive introduction to this novel and revolutionary tool, presenting both concepts and application examp...
In this new edition of a bestseller, all the contents have been updated and new material has been added, especially in the areas of toxicity testing and high throughput analysis. The authors, all of t...
Cocaine use in Britain has caused much concern but its extent has been unknown. Users are still quite affluent, but when cocaine hits street level - as it is predicted to do in the late 1990s - proble...
In present-day drug discovery, bioactive molecules with a sought-after physiological effect are identified by screening large libraries of drug candidates for a quantifiable effect on a biological tar...
By delving beyond the genomic information, proteomics can address problems that are inaccessible to conventional genomics studies. These new and powerful analytical techniques open up new possibilitie...
Summary This report represents the conclusions of a Joint FAO/WHO Expert Committee convened to evaluate the safety of residues of certain veterinary drugs in food and to recommend maximum levels for s...
A panel of researchers and experts from leading universities and major pharmaceutical companies from all over the world systematically describe cutting-edge experimental protocols for the early in vit...
A working guide to the use of drugs in the treatment of urological disease The content is arranged so that the busy urologist can go quickly and easily to the relevant section Coverage of treatment is...
Discover how biomarkers can boost the success rate of drug development efforts As pharmaceutical companies struggle to improve the success rate and cost-effectiveness of thedrug development process, b...
This book provides a comprehensive review on the emerging and dynamic field of nuclear receptor-mediated gene regulation in drug metabolism. Information in this book equips drug development scientists...
Covering every essential element in the development of chiral products, this reference provides a solid overview of the formulation, biopharmaceutical characteristics, and regulatory issues impacting ...
This second edition of the highly praised Drug Interaction in Infectious Diseases includes all the major recent advances in the understanding of drug interactions, with emphasis on the many new drugs ...
Informatics and robotics are the workhorses of a technological revolution in drug research. On them are based combinatorial chemistry which yields compounds by the many thousands, and high-throughput ...
There is a real need for a good up-to-date book on the design and analysis of bioequivalence studies and this book fulfills it by providing an overview of available methods, adopting a practical appro...
Presents technical approaches used in systems level drug abuse and addiction researchOffers detailed technical descriptions of applicable procedures and methodologies Includes standard procedures for ...
Human Drug Metabolism, An Introduction, Second Edition provides an accessible introduction to the subject and will be particularly invaluable to those who already have some understanding of the life s...
Over the past two decades, tremendous advances have been made in the field of cancer drug discovery, particularly in the area of molecular and genetic models and technologies, many of which have been ...
Comparative Genomics and Proteomics in Drug Discovery gives an overview of how emerging genomic and proteomic technologies are making significant contributions to global drug discovery programmes, and...
Principles of Drug Therapy, Second Edition provides comprehensive coverage of current drug therapy in neurology while providing the background information that neurologists and other clinicians need t...
This book addresses the needs of drug discovery scientists and managers planning to initiate their own toxicogenomics programs or acquire access to an existing database. The book introduces readers to...
Enables you to detect, identify, and characterize hundreds of drugs that may be used by athletes Mass spectrometry has become essential to sports drug testing. This book examines both the principles o...
"Short Protocols in Pharmacology and Drug Discovery" provides condensed descriptions of more than 350 methods compiled from the successful title "Current Protocols in Pharmacology". The book is specif...
Examines the emerging therapeutic role of TRPV1 TRPV1 is considered an integrator of noxious stimuli and therefore may be at a crossroads for pain transmission pathways. Because of its potential for m...
Substantial morbidity and mortality remains associated with thrombotic events has stimulated the rapid expansion of the available armamentarium to combat pathologic thrombosis. Pathologic thrombosis ...
Presents the most recent trends based on significant advances made in genomics, proteomics, and bioinformatics since the 1970sExamines genomic correlations between different organisms and various mode...
This timely reference discusses mass spectrometry in drug metabolism and pharmacokinetic studies. With contributions by professionals from the pharmaceutical industry, this book begins with a review o...
Beverly Teicher and a panel of distinguished investigators survey the state-of-the-art of antiangiogenesis research from the lab bench to clinical trials. Timely and authoritative, the contributors su...