This book addresses the needs of drug discovery scientists and managers planning to initiate their own toxicogenomics programs or acquire access to an existing database. The book introduces readers to...
Enables you to detect, identify, and characterize hundreds of drugs that may be used by athletes Mass spectrometry has become essential to sports drug testing. This book examines both the principles o...
"Short Protocols in Pharmacology and Drug Discovery" provides condensed descriptions of more than 350 methods compiled from the successful title "Current Protocols in Pharmacology". The book is specif...
Examines the emerging therapeutic role of TRPV1 TRPV1 is considered an integrator of noxious stimuli and therefore may be at a crossroads for pain transmission pathways. Because of its potential for m...
Substantial morbidity and mortality remains associated with thrombotic events has stimulated the rapid expansion of the available armamentarium to combat pathologic thrombosis. Pathologic thrombosis ...
Presents the most recent trends based on significant advances made in genomics, proteomics, and bioinformatics since the 1970sExamines genomic correlations between different organisms and various mode...
In everyday practice, anaesthetists can make use of a wide range of drug treatments, and require readily available and accessible information on the appropriate drug to use in any given situation. The...
This timely reference discusses mass spectrometry in drug metabolism and pharmacokinetic studies. With contributions by professionals from the pharmaceutical industry, this book begins with a review o...
Beverly Teicher and a panel of distinguished investigators survey the state-of-the-art of antiangiogenesis research from the lab bench to clinical trials. Timely and authoritative, the contributors su...
Knowledge of the basic mechanisms of human disease is essential for any student or professional engaged in drug research and development. Functional gene analysis (genomics), protein analysis (proteom...
Imaging is a key area of translational research that provides a unique bridge from the laboratory to the clinic as the same techniques and technologies can applied across the various phases of drug de...
Covering the latest advances in CNS drug development, this book will guide all those involved in pre-clinical to early clinical trials. The authors describe how recent innovations can accelerate the d...
Molecular pathology offers tools and techniques that can greatly enhance the drug discovery and development process, helping to make the promises of personalized medicine a reality. Molecular Patholog...
Contains detailed protocols of assay methodologies that facilitate setting up specific assaysUtilizes examples that illustrate the use of a particular assay methodology in context and demonstrate how ...
Demonstrating current and potential uses of in vivo MR techniques in the drug discovery and development processes, this guidediscusses applications for specific disease areas, emphasizing the advantag...
Numerous treatment options are available to intensive care staff; this requires detailed knowledge of routes of administration and contra-indications to use in certain clinical conditions. Now in its ...
Written by a well-known lecturer and consultant to the pharmaceutical industry, this book focuses on the pharmaceutical non-statistician working within a very strict regulatory environment. Statistica...
Regularly reviewing the "state-of-the-art" developments in the antiviral drug research field, this latest volume spans the conceptual design and chemical synthesis of new antiviral compounds. It discu...
Advances in genomics and combinatorial chemistry during the past two decades inspired innovative technologies and changes in the discovery and pre-clinical development paradigm with the goal of accele...
Written by scientists in the field of delivery of protein and peptide drugs to tumors for cancer therapy, this book provides a broad introduction to the field, with discussion by key experts on the ph...
Drugs and Behavior: An Introduction to Behavioral Pharmacology
Electrochemical Detection in HPLu Analysis of Drugs and Poisons is the first monograph devoted to the application of this mode of analysis to the assay of exogenous compounds such as drugs in biologic...
Elsevier now offers a series of derivative works based on the acclaimed Meyler's Side Effect of Drugs, 15th Edition. These individual volumes are grouped by specialty to benefit the practicing biomedi...
One of the main causes of failure in the treatment of breast cancer is the intrinsic presence of, or development of, drug resistance by the cancer cells. Recent studies on the mechanisms of cancer dru...
There has been significant progress in the development of targeted therapy drugs that act specifically on certain cancers, and that minimize damage to normal cells. Oncologists and cancer researchers ...